1. Spoleto Festival USA

The Buzz -- Beginning on Memorial Day weekend and lasting a little over two weeks, Spoleto is undeniably one of the best arts festivals in the country. The visual arts are represented in several special exhibits and an arts and crafts fair, and performance venues are scattered across the city. You can enjoy world-class performances in classical music, ballet, opera, and jazz, courtesy of both national and international performers. If you've never experienced Spoleto, be sure to schedule your next trip to Charleston during its run. The Spoleto Box Office is open from mid-April through the last day of the festival.