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1. High Cotton

550 S Main St, RiverPlace, Greenville, SC 29601 · 864-335-4200

User Rating:  Rating: 3 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining: None

DOWNTOWN. When news broke that this Charleston standout was planning to open a Greenville location, the public rejoiced – and for good reason. It's widely known that the folks behind High Cotton know how to impress, and that's just what this multilevel dining room does with its soaring glass walls and cool, contemporary space. Take in the view of the Reedy River as you savor an appetizer of seared Hudson Valley foie gras or jumbo lump crab Oscar. From there, main courses like sliced venison medallions, butternut squash, buttermilk-brined free range chicken or cornbread-crusted flounder should (and do) warrant your undivided attention. Outstanding wine list.

2. Wine Cafe at Northampton Wines

211A E Broad St, Greenville, SC 29601 · 864-271-3919

User Rating:  Rating: 5 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining: None

DOWNTOWN. This restaurant developed from Northampton's much-applauded wine shop and is a natural outgrowth of its focus on quality goods. The bright, narrow space is quiet and decidedly unpretentious, so it's a great place for a date or a low-key celebration. The menu boasts dishes like roasted pheasant, ale-braised rabbit, coriander-crusted tuna loin, and twin tournedos with basil pesto duxelles. Each dish is accompanied by suggestions for wine pairings, or you can choose a bottle from the shop and have it served with your meal. Special wine dinners are available regularly. Prixe-fixe: $98 with wine.

3. 33 Liberty

33 Liberty Ln, Greenville, SC 29607 · 864-370-4888

User Rating:  Rating: 5 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Required
Dress: BCBC: Business Casual
Outdoor Dining: None

LAURENS ROAD. The culinary child of John and Amy Malik, 33 Liberty has earned a glowing reputation for its accomplished New American fare. Premium ingredients and a sure hand result in fantastic courses. Representative dishes include fried quail with sweet potato gratin, braised veal osso bucco, and sauteed fish with a polenta cake. A terrific, affordable wine list, great service, and a chef's table heighten the appeal.

4. Devereaux's

25 E Court St, Greenville, SC 29601 · 864-241-3030

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining:

DOWNTOWN. Set in a turn-of-the-century factory, Devereaux's sets a romantic scene, juxtaposing candlelight and white linens with aged brick and wooden beams. The upscale establishment is a family affair, and the time-tested relationships add a certain ease to operations. Great atmosphere is an ideal complement to the excellent food, which includes pancetta-wrapped Atlantic halibut, bourbon brined pork loin, Asian-scented rack of lamb, and Amish chicken breast with heirloom corn polenta. A chef's tasting menu and a lively bar scene add weight to an already strong enterprise.

5. Augusta Grill

1818 Augusta St, Greenville, SC 29605 · 864-242-0316

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Available
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining: None

AUGUSTA ROAD. Since the doors opened late in 1993, this bistro-style restaurant has become a neighborhood mainstay. Its focus on innovative American cuisine results in dishes such as pecan crusted trout, grilled salmon salad, and penne pomodoro. An extensive wine list and soothing piano bar add to the upscale ambiance. Tempting dessert menu includes rich cobblers, delicate cakes and refreshing sorbets. Attentive, unobtrusive service.

6. Sassafras Southern Bistro

103 N Main St, Piazza Bergamo, Greenville, SC 29601 · 864-235-5670

User Rating:  Rating: 3 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining:

DOWNTOWN. Set on a courtyard just off Main Street, Sassafras occupies a former cigar warehouse, whose aged brick and worn timbers add a textural note that's complemented by original art. Comfortable and upscale, the restaurant specializes in gourmet Southern fare, especially that tinged with Low Country accents. Start with a basket of sweet potato fries or a napoleon of fried green tomatoes and pimiento cheese before giving yourself over to prosciutto-wrapped scallops, shrimp and grits, crab cakes, pecan-crusted rainbow trout, or even fried chicken livers. More standard options include steaks, tuna, grilled salmon, and pork loin. Outdoor dining and a great bar scene heighten the allure.

7. Soby's

207 S Main St, Greenville, SC 29601 · 864-232-7007

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining:

DOWNTOWN. This Main Street staple is one of Greenville's favorites. The new-south cuisine includes such tempting entrees as New Orleans BBQ shrimp and grits, grilled smoked pork loin, and crab cake remoulade. The desserts are sumptuous, especially the banana cream pie. Soby's also offers a lively bar scene which attracts Greenville's after-business crowd with its extensive wine list and after dinner drink options. Very knowledgeable and friendly staff.

8. Latitude

631 S Main St, Greenville, SC 29601 · 864-467-1101

User Rating:  Rating: 5 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining:

DOWNTOWN. The interior is upscale-European with a nautical theme. The entrees are works of art created by their master chef. Leave room for their delectable desserts, all of which are prepared fresh as you dine.

9. Peppermill

30 Orchard Park Dr, Greenville, SC 29615 · 864-288-9320

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining: None

HAYWOOD ROAD. This fine dining establishment offers Ccontinental cuisine at its best. Great service, elegant surroundings, and a wine cellar with over 1400 wines make this a true dining experience. Have Steak Diane prepared right at the table or enjoy your choice of the finest cuts of steak, seafood, lamb or pork.

10. American Grocery Restaurant

732 S Main St, Greenville, SC 29601 · 864-232-7665

User Rating:  Rating: 3 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining: None

WEST END. Fine, seasonal cuisine is the hallmark of this quaint dining room, occupying a refurbished storefront in the West End. Its talented kitchen staff use ingredients from regional farms to create breathtaking concoctions that might include garden ratatouille with herbed couscous, or venison with baby Swiss chard, parsnip puree and Cumberland sauce. A delightful selection of artisan wines and Leopard Forest coffee enhance the meal.

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