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1. High Cotton

550 S Main St, RiverPlace, Greenville, SC 29601 · 864-335-4200

User Rating:  Rating: 3 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining: None

DOWNTOWN. When news broke that this Charleston standout was planning to open a Greenville location, the public rejoiced – and for good reason. It's widely known that the folks behind High Cotton know how to impress, and that's just what this multilevel dining room does with its soaring glass walls and cool, contemporary space. Take in the view of the Reedy River as you savor an appetizer of seared Hudson Valley foie gras or jumbo lump crab Oscar. From there, main courses like sliced venison medallions, butternut squash, buttermilk-brined free range chicken or cornbread-crusted flounder should (and do) warrant your undivided attention. Outstanding wine list.

2. Restaurant O

116 S Main St, Greenville, SC 29601 · 864-331-0007

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining:

DOWNTOWN. A dramatic interplay of glass, steel and concrete establish a hip, high-class ambience in one of Greenville's most cosmopolitan restaurants. Big-city style pervades both the dining room and the mezzanine lounge – a perfect place to impress clients or honor a special occasion. While aged, hand-cut steaks are the menu's spectacular focus, patrons can also treat themselves to items like five-spice seared scallops, chipotle barbecue-glazed short ribs, and the restaurant's giant crab cake. The wine list gives preference to reds from California and Europe. A great place just for drinks too.

3. Wine Cafe at Northampton Wines

211A E Broad St, Greenville, SC 29601 · 864-271-3919

User Rating:  Rating: 5 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining: None

DOWNTOWN. This restaurant developed from Northampton's much-applauded wine shop and is a natural outgrowth of its focus on quality goods. The bright, narrow space is quiet and decidedly unpretentious, so it's a great place for a date or a low-key celebration. The menu boasts dishes like roasted pheasant, ale-braised rabbit, coriander-crusted tuna loin, and twin tournedos with basil pesto duxelles. Each dish is accompanied by suggestions for wine pairings, or you can choose a bottle from the shop and have it served with your meal. Special wine dinners are available regularly. Prixe-fixe: $98 with wine.

4. 33 Liberty

33 Liberty Ln, Greenville, SC 29607 · 864-370-4888

User Rating:  Rating: 5 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Required
Dress: BCBC: Business Casual
Outdoor Dining: None

LAURENS ROAD. The culinary child of John and Amy Malik, 33 Liberty has earned a glowing reputation for its accomplished New American fare. Premium ingredients and a sure hand result in fantastic courses. Representative dishes include fried quail with sweet potato gratin, braised veal osso bucco, and sauteed fish with a polenta cake. A terrific, affordable wine list, great service, and a chef's table heighten the appeal.

5. Devereaux's

25 E Court St, Greenville, SC 29601 · 864-241-3030

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining:

DOWNTOWN. Set in a turn-of-the-century factory, Devereaux's sets a romantic scene, juxtaposing candlelight and white linens with aged brick and wooden beams. The upscale establishment is a family affair, and the time-tested relationships add a certain ease to operations. Great atmosphere is an ideal complement to the excellent food, which includes pancetta-wrapped Atlantic halibut, bourbon brined pork loin, Asian-scented rack of lamb, and Amish chicken breast with heirloom corn polenta. A chef's tasting menu and a lively bar scene add weight to an already strong enterprise.

6. Ristorante Bergamo

100 N Main St, Greenville, SC 29601 · 864-271-8667

User Rating:  Rating: 5 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining: None

DOWNTOWN. A pale, shining environment only serves to highlight the exceptional northern Italian cuisine served at Bergamo's. Always prepared with the freshest ingredients, this is some of the best Italian in the Upstate. Pastas, steaks and seafood are satisfying and robust. Salads and antipasti showcase a medley of flavors, and the simple desserts perfectly complete the richness of a good meal. Definitely one to try.

7. Augusta Grill

1818 Augusta St, Greenville, SC 29605 · 864-242-0316

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Available
Dress: B, BCB: Business
BC: Business Casual
Outdoor Dining: None

AUGUSTA ROAD. Since the doors opened late in 1993, this bistro-style restaurant has become a neighborhood mainstay. Its focus on innovative American cuisine results in dishes such as pecan crusted trout, grilled salmon salad, and penne pomodoro. An extensive wine list and soothing piano bar add to the upscale ambiance. Tempting dessert menu includes rich cobblers, delicate cakes and refreshing sorbets. Attentive, unobtrusive service.

8. Sassafras Southern Bistro

103 N Main St, Piazza Bergamo, Greenville, SC 29601 · 864-235-5670

User Rating:  Rating: 3 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining:

DOWNTOWN. Set on a courtyard just off Main Street, Sassafras occupies a former cigar warehouse, whose aged brick and worn timbers add a textural note that's complemented by original art. Comfortable and upscale, the restaurant specializes in gourmet Southern fare, especially that tinged with Low Country accents. Start with a basket of sweet potato fries or a napoleon of fried green tomatoes and pimiento cheese before giving yourself over to prosciutto-wrapped scallops, shrimp and grits, crab cakes, pecan-crusted rainbow trout, or even fried chicken livers. More standard options include steaks, tuna, grilled salmon, and pork loin. Outdoor dining and a great bar scene heighten the allure.

9. Gerard's

102 E Poinsett St, Greer, SC 29651 · 864-879-0070

User Rating:  Rating: 5 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BCBC: Business Casual
Outdoor Dining:

GREER. Recipient of much praise and local buzz, Gerard's hits the mark with its contemporary Italian cuisine. The open, elegant space in a restyled storefront features hardwood floors, brick walls, and pools of romantic, ambient light. The outdoor dining area, protected by an arbor, is surrounded by lush seasonal plantings. The menu is executed with a sure hand and features pastas, seafood, veal, lamb, beef, duck, and chicken. Representative dishes include pancetta-wrapped pork tenderloin with pear compote and seared scallops with sherry cream, baby spinach, and risotto Milanese. The wine list specializes in Italian and Californian vintages. Wonderful for special occasions.

10. Chophouse '47

36 Beacon Dr, Greenville, SC 29615 · 864-286-8700

User Rating:  Rating: 4 / 5   (Rate It)

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Avg. Entrée: $$$16 - $30
Reservations: Recommended
Dress: BB: Business
Outdoor Dining: None

PELHAM. Chophouse '47 hearkens back to the cozy, masculine eateries of the World War II era – subdued lighting, hardwood floors, dark-stained tables and chairs, and the Chairman himself crooning in the background. Kick off your meal with rich oysters Rockefeller or shellfish bisque, then move on to more serious fare – a delicious 14-oz New York strip, Tenderloin Towers wrapped in a giant onion ring, or a 38-oz Portherhouse for Two. Add to the mix a superb international wine list and a dessert menu that features fine cigars, and you've got the perfect place to entertain clients or celebrate a big event.

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