7. Medtronic Twin Cities Marathon

The Buzz -- With a scenic route along area lakes and the Mississippi River and an average temperature in the mid 60s, this appealing race is often considered the nation's "most beautiful urban marathon." First established in 1982, it united separate races in Minneapolis and St. Paul; now, the marathon begins in the first city and finishes in the latter, at the State Capitol. Accompanying the big event are other weekend activities, including 10-mile and 5K races, a fitness expo, and family-friendly competitions.