Let's be honest: when it comes to a wide selection of exciting nightlife opportunities, almost no city in the world can touch San Francisco.
With all the tech money pouring in, the Mission District has become as wild and as daring as ever. The smells and sights of Chinatown remains just as exotic, too, and what can beat a romantic night strolling up Columbus Avenue of North Beach past adorable Italian cafes?
Throw in a world-class symphony and opera, plus a museum that offers the hippest, night-time adult programming around, and there's literally something for everyone in San Francisco.
But there's definitely something to be said for getting that party started as soon as possible.
Case in point: you've just walked out of a 49ers game. You are a big-time fan, and they have demolished their opponent. You are part of a sea of 49ers red jerseys pumped to keep that boisterous tailgate party that started well before kick-off going all night. What do you do?
You check out our list of local bars and nightclubs, all of them eager to meet your needs. They might not all be the fanciest of establishments, but they are close by and staffed by hard-core football fans who want to celebrate just as bad as you.
And if you happen to be a fan of the 49er's opponent that day, don't worry: all is fair in love and football. Especially after the game when some serious partying should be enjoyed by all.