Open 365 days a year until 4AM, The Duplex is not your grandmother's piano bar. Instead, colorful characters from New York and beyond show up for the opportunity to get in front of the crowd for a performance. Drag queens mix-and-mingle with straight guys and gays alike, livening up the atmosphere and adding an extra dash of playfulness to the vibe. Unlike other places on this list, The Duplex supports a come-as-you-are, open door policy, so you won't have to worry about sporting your Sunday best to get inside. Once there, try your fingers on the keys or grab hold of the mic – it's about to be a wild ride.